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Leo Pharmaceutical

LEO Pharmaceutical is a world leader in topical dermatology medicines. The LEO plant in Dublin produces a wide variety of medicines for the treatment of skin conditions such as eczema and psoriasis as well as veterinary products.

Forecasts by Dalco Nitrogen Systems, exclusive distributors of domnick hunter MAXIGAS nitrogen generators in Ireland, indicated the company could make savings by switching its nitrogen supply from bulk liquid to PSA nitrogen.

LEO installed two N2MAX110 MAXIGAS nitrogen generators, in a turnkey solution consisting of a pre-fabricated room with a domnick hunter pretreatment package that ensures compressed air quality by filtering and drying air before it enters the generator. The system delivers a nitrogen flowrate of 55m3/hr.

Every new piece of equipment at LEO undergoes a risk analysis check, because nitrogen in confined spaces can pose a risk of oxygen depletion, the self contained room includes oxygen analysers with visual and audible alarms that remove any health and safety risks.

Nitrogen is absolutely production critical to the plant that operates 24 hours a day, to cope with any peaks in demand, the bespoke solution includes a 10,000 litre storage vessel. In order to comply with GMP regulations a thermal mass flow meter, a moisture meter and a sterile dust filter that removes particles right down to 0.01 micron in size were also installed. Together, these bespoke features continuously monitor nitrogen purity into the plant. Dalco were also able to certify nitrogen purity.

Prior to installation, LEO was spending about £100,000 per year on liquid nitrogen and is now spending £20,000 a year, that’s a massive saving of 80%.

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Dalco Nitrogen Systems

Ireland: Dunshaughlin, Co. Meath T: +353 (0)18250768 F:+353 (0)18250769

U.K.: Northumberland T: +353 (0)18250768 F:+353 (0)18250769

Australia: 153 Burnside Rd., Bannockburn, Victoria 3331 T: +61 0) 352812951